| POS. | EMPRESA | POBLACION | VENTAS | AÑO |
| 301 | HIERROS SANCHEZ SL | TORRE-PACHECO | 15.644.601,88 € | 2010 |
| 302 | OBRAS Y SERVICIOS MONEO SL | MOLINA | 15.643.927,92 € | 2010 |
| 303 | VERDIMED SA | SAN JAVIER | 15.634.544,87 € | 2010 |
| 304 | BODEGAS 1890 SA | JUMILLA | 15.625.725,77 € | 2010 |
| 305 | CITRICOS INDUSTRIALES CUELLO SL | MURCIA | 15.617.971,15 € | 2011 |
| 306 | AGRICOLA SANTA EULALIA SL | TOTANA | 15.416.874,82 € | 2011 |
| 307 | ASFALTOS DEL SURESTE SA | LOMA DE ARRIBA | 15.415.640,68 € | 2011 |
| 308 | EMDICO SA | CARTAGENA | 15.385.705,42 € | 2010 |
| 309 | PRONUMANTIS SL | MURCIA | 15.380.952,00 € | Ant. |
| 310 | E.S.S.P. ESPAÑA 2000 SL | AGUILAS | 15.319.639,09 € | 2011 |
| 311 | SA DE ELECTRONICA SUBMARINA | CARTAGENA | 15.258.344,00 € | 2011 |
| 312 | FROET SERVICIOS SA | MURCIA | 15.160.198,93 € | 2010 |
| 313 | FRUTAS EL DULZE SL | SAN JAVIER | 15.149.360,87 € | 2010 |
| 314 | TAPIZADOS FAMA SL | YECLA | 15.045.834,87 € | 2010 |
| 315 | SANCHEZ MORALES HERMANOS SL | PUERTO LUMBRERAS | 15.045.796,06 € | 2010 |
| 316 | INTERSOLAZ SL | TORRE-PACHECO | 14.990.848,06 € | Ant. |
| 317 | ZAPATA Y COMPAÑIA SL | MURCIA | 14.803.071,00 € | 2010 |
| 318 | EDIFICACIONES SODELOR SL | LORCA | 14.716.801,31 € | 2010 |
| 319 | FRUTAS SELECTAS MURCIANAS SA | MURCIA | 14.699.615,33 € | 2010 |
| 320 | PIENSOS Y GANADOS PERDIGON SL | LOS GARRES | 14.616.717,32 € | 2011 |
| 321 | FAJ INGENIEROS SA | MURCIA | 14.596.133,67 € | Ant. |
| 322 | NAVARRO DE HARO SL | LORCA | 14.564.320,31 € | 2011 |
| 323 | ATUNES DE LEVANTE SA | CARTAGENA | 14.542.275,78 € | Ant. |
| 324 | NEW CONCISA SL | CIEZA | 14.523.454,17 € | 2011 |
| 325 | EXCOMTI DESARROLLOS SL | SANGONERA LA SECA | 14.516.571,72 € | 2011 |
| 326 | JOSE DIAZ GARCIA SA | SAN JAVIER | 14.508.705,33 € | 2011 |
| 327 | HORTOFRUTICOLA DE VEGETALES SL | FUENTE ALAMO | 14.483.784,82 € | 2010 |
| 328 | GANADOS SAN ANTONIO SL | FUENTE ALAMO | 14.468.991,56 € | 2011 |
| 329 | MARCA PROTECCION LABORAL SL | CARTAGENA | 14.298.597,00 € | 2010 |
| 330 | DESTILERIAS MUÑOZ GALVEZ SA | MURCIA | 14.294.164,42 € | 2010 |
| 331 | MOSCA MARITIMO SL | MOLINA | 14.276.238,82 € | 2010 |
| 332 | METROPOLITANA DE CONTRATACIONES S.L | MURCIA | 14.251.200,49 € | Ant. |
| 333 | DISTRICAM LICORES SL | LORCA | 14.142.152,71 € | 2011 |
| 334 | FRIO CABALLERO SL | SANGONERA LA SECA | 14.010.876,26 € | 2010 |
| 335 | GDF SUEZ CARTAGENA OPERATIONS SL | CARTAGENA | 13.990.787,00 € | 2010 |
| 336 | NUEVA ESCALA 1 50 SL | MOLINA | 13.923.661,29 € | Ant. |
| 337 | CORDITRANS MURCIA SL | MURCIA | 13.915.319,92 € | 2011 |
| 338 | AGROQUIMICOS LOS TRIVIÑOS SL | TORRE-PACHECO | 13.865.960,73 € | 2011 |
| 339 | HERMANOS JIMENEZ CAYUELA SL | LORCA | 13.851.359,99 € | 2011 |
| 340 | SOLTEC ENERGIAS RENOVABLES SL | MOLINA | 13.824.846,45 € | 2011 |
| 341 | AREAS DE SERVICIO LOS CALZONES SL | ABANILLA | 13.746.856,23 € | 2011 |
| 342 | HIDA ALIMENTACION SA | MURCIA | 13.680.489,19 € | 2010 |
| 343 | FRUTAS NATURALES SA | SAN PEDRO | 13.654.987,65 € | 2010 |
| 344 | TRANSPORTES QUEVEDO SA | MURCIA | 13.637.583,97 € | 2011 |
| 345 | AGRICOLA DURAN SL | MAZARRON | 13.518.316,50 € | 2010 |
| 346 | TRANSGALLEGO LOGISTIC SL | MURCIA | 13.502.004,54 € | 2011 |
| 347 | GONZALEZ SOTO SA | LA UNION | 13.452.068,69 € | 2010 |
| 348 | FRUYPER SA | BENIAJAN | 13.437.385,34 € | 2011 |
| 349 | PATRICIO NAVARRO ROBLES SL | SAN PEDRO | 13.433.405,27 € | 2011 |
| 350 | A.P.M. IMPULSE SL | BULLAS | 13.413.490,35 € | 2011 |
