| POS. | EMPRESA | POBLACION | VENTAS | AÑO |
| 51 | CULMAREX SA | AGUILAS | 59.740.027,00 € | 2011 |
| 52 | DIEGO ZAMORA SA | CARTAGENA | 56.913.789,00 € | 2010 |
| 53 | DISFRIMUR SL | SANGONERA LA SECA | 56.668.578,65 € | 2011 |
| 54 | GRUPO PALOMA SA | MAZARRON | 56.507.510,00 € | 2011 |
| 55 | PC COMPONENTES Y MULTIMEDIA SL | ALHAMA | 56.083.113,56 € | 2011 |
| 56 | PLASTICOS ROMERO SA | MOLINA | 56.022.234,36 € | 2010 |
| 57 | DEPAU SISTEMAS SL | MURCIA | 55.992.858,82 € | 2010 |
| 58 | LIMCAMAR SL | MURCIA | 55.099.953,13 € | 2011 |
| 59 | PLASBEL PLASTICOS SA | ALCANTARILLA | 52.335.498,82 € | 2011 |
| 60 | EL CIRUELO SL | ALHAMA | 52.038.890,21 € | 2011 |
| 61 | GEHRLICHER SOLAR ESPAÑA SL | BULLAS | 51.498.892,00 € | 2011 |
| 62 | PEINSA 97 SL | SAN PEDRO | 51.242.447,03 € | Ant. |
| 63 | VISIONARIA SL | MURCIA | 51.169.178,00 € | 2010 |
| 64 | CENTRAL QUESERA MONTESINOS SL | FUENTE DEL PINO | 51.097.031,14 € | 2011 |
| 65 | FRANCISCO ARAGON SL | MOLINA | 50.755.440,86 € | 2011 |
| 66 | INTERNACIONALES PEDREÑO SA | ESTRECHO | 50.182.671,43 € | 2010 |
| 67 | SOGESOL SA | TORRE-PACHECO | 49.860.124,00 € | 2011 |
| 68 | XTI FOOTWEAR SL | YECLA | 49.262.116,38 € | 2011 |
| 69 | SONIFER SA | MURCIA | 48.588.868,92 € | 2011 |
| 70 | CONSORCIO DE EXPORTACION AMACO SL | MURCIA | 47.705.848,80 € | 2010 |
| 71 | HPLUS INTERNACIONAL SA | SANTOMERA | 46.901.979,24 € | 2011 |
| 72 | NAGARMUR SL | CHURRA | 46.420.769,35 € | 2011 |
| 73 | CASH LEVANTE SL | SANTOMERA | 46.229.676,79 € | 2011 |
| 74 | PIENSOS CARTAGENA SL | LOS DOLORES | 45.768.426,83 € | 2011 |
| 75 | CAMPILLO PALMERA SA | MOLINA | 45.305.996,87 € | 2011 |
| 76 | COMERCIAL DIMOVIL SL | MOLINA | 44.494.555,14 € | 2011 |
| 77 | TRADING SURESTE SL | LORQUI | 43.698.312,17 € | 2011 |
| 78 | JUSTO Y MANOLI SL | MAZARRON | 43.565.851,86 € | Ant. |
| 79 | HIERROS IBAÑEZ SA | SAN GINES | 43.545.896,86 € | 2011 |
| 80 | HIJOS DE JUAN PUJANTE SA | MURCIA | 42.732.775,60 € | 2011 |
| 81 | GINES HUERTAS INDUSTRIALES S.L | CARTAGENA | 42.488.049,38 € | 2011 |
| 82 | PUJANTE MOTOR SL | MURCIA | 41.913.553,35 € | 2010 |
| 83 | ITETE SA | MURCIA | 41.886.736,72 € | 2010 |
| 84 | DIMOVIL SA | MOLINA | 41.400.727,14 € | 2010 |
| 85 | RAMON SABATER SA | CABEZO DE TORRES | 40.981.562,41 € | 2011 |
| 86 | ETOSA OBRAS Y SERVICIOS SA | TOTANA | 40.853.927,93 € | 2011 |
| 87 | VINOS Y LICORES GAMBIN S.L | MOLINA | 40.708.724,34 € | 2011 |
| 88 | FRUTAS ESTHER SA | ABARAN | 40.296.235,44 € | 2010 |
| 89 | DIFRUSA EXPORT SA | CARTAGENA | 40.008.588,15 € | 2011 |
| 90 | TSI PLUS SL | MURCIA | 39.551.756,41 € | 2010 |
| 91 | GOR FACTORY SA | FORTUNA | 39.384.559,10 € | 2011 |
| 92 | DIEGO LOPEZ LOPEZ SL | LORCA | 38.979.821,54 € | 2011 |
| 93 | AUTO SPORT S CAB SL | MURCIA | 38.891.012,28 € | Ant. |
| 94 | AGROMARK SL | TORRE-PACHECO | 38.462.517,00 € | 2011 |
| 95 | SOL Y TIERRA CAMPO DE CARTAGENA SL | TORRE-PACHECO | 37.362.433,86 € | 2011 |
| 96 | COFRUTOS SA | CEHEGIN | 37.274.002,92 € | 2010 |
| 97 | ULTRACONGELADOS AZARBE SA | MURCIA | 36.759.150,03 € | 2010 |
| 98 | PREMIUM INGREDIENTS SL | MURCIA | 36.471.710,99 € | 2011 |
| 99 | JIMENEZ GODOY SA | MURCIA | 35.126.450,85 € | 2010 |
| 100 | PLASTICOS DE MOLINA SL | MOLINA | 34.779.639,19 € | 2011 |
