| POS. | EMPRESA | POBLACION | VENTAS | AÑO |
| 101 | R1 GAMA CAMIONES 2010 SL | MOLINA | 34.527.417,50 € | 2011 |
| 102 | GRUPO DE TELEVISION DE MURCIA SA | MURCIA | 34.301.528,00 € | 2010 |
| 103 | KERNEL EXPORT SL | LOS ALCAZARES | 34.231.211,78 € | 2011 |
| 104 | HORTOFRUTICOLA MENDEZ SA | MAZARRON | 34.025.530,80 € | Ant. |
| 105 | TRANSPORTES APICHE SL | LORCA | 33.250.300,97 € | 2010 |
| 106 | CORVERA GOLF & COUNTRY CLUB SL | MURCIA | 32.880.112,26 € | 2010 |
| 107 | NUEVAS ENERGIAS DEL SURESTE SA | PUERTO LUMBRERAS | 32.691.577,00 € | Ant. |
| 108 | AGROURBANA CARTHAGO SL | LA APARECIDA | 32.535.305,68 € | 2010 |
| 109 | DURAN & PASCUAL MARKETING S.L | MAZARRON | 32.454.505,97 € | Ant. |
| 110 | ESTRELLA DE LEVANTE SA | MURCIA | 31.913.376,23 € | 2010 |
| 111 | POLIMUR SA | LORQUI | 31.486.723,62 € | 2011 |
| 112 | ALCURNIA ALIMENTACION SL | MOLINA | 31.419.196,63 € | 2011 |
| 113 | CARNICAS AZOR SL | TORRE-PACHECO | 31.276.348,02 € | Ant. |
| 114 | GOLDEN FOODS SA | LAS TORRES | 31.241.004,91 € | 2011 |
| 115 | INGENIERIA Y COM. DEL GAS SA | MURCIA | 31.011.529,82 € | 2010 |
| 116 | HIJOS DE MANUEL LUCAS SL | BARQUEROS | 31.004.846,32 € | 2011 |
| 117 | LICARSA SA | CARTAGENA | 30.995.000,00 € | 2010 |
| 118 | J. PUJANTE SA | MURCIA | 30.537.172,25 € | 2010 |
| 119 | MARIN MONTEJANO SA | LORQUI | 30.412.697,20 € | Ant. |
| 120 | EUPINCA SA | CARTAGENA | 30.276.964,33 € | 2011 |
| 121 | CEPSA COMERCIAL ESTE SA | BARRIO PERAL | 30.126.984,97 € | 2010 |
| 122 | BAHIA DE MAZARRON SA | MAZARRON | 29.998.224,20 € | Ant. |
| 123 | PLASTICOS DEL SEGURA SL | BENIAJAN | 29.887.869,86 € | 2011 |
| 124 | GERIMPORT SL | MURCIA | 29.826.949,80 € | 2011 |
| 125 | GRUPO ROSEGAR SL | BENIEL | 29.731.769,28 € | 2010 |
| 126 | ALMACENES BEMALU SA | MAZARRON | 29.640.009,05 € | 2011 |
| 127 | VIVER-ATUN CARTAGENA SA | CARTAGENA | 29.292.742,20 € | Ant. |
| 128 | IBERCHEM SA | ALCANTARILLA | 29.286.130,00 € | 2010 |
| 129 | DOFASUM SL | LORCA | 29.259.302,63 € | Ant. |
| 130 | SAECO | MOLINA | 28.800.166,71 € | 2010 |
| 131 | LA MANGA CLUB SL | CARTAGENA | 28.740.828,26 € | 2010 |
| 132 | DALLAND HYBRID ESPAÑA S A | MURCIA | 28.703.374,37 € | 2010 |
| 133 | AUPESAN SL | MURCIA | 28.598.710,01 € | 2011 |
| 134 | MURGACA SA | CARTAGENA | 28.545.901,69 € | 2010 |
| 135 | SUCESORES DE LUIS CREMADES SA | ALCANTARILLA | 28.535.861,07 € | 2010 |
| 136 | TRANSPORTES CALICHE SL | TORRE-PACHECO | 28.387.850,87 € | 2011 |
| 137 | MARIN JIMENEZ HERMANOS SA | ARCHIVEL | 28.212.975,00 € | 2011 |
| 138 | POLARIS DESARROLLO SL | TORRE-PACHECO | 28.197.085,00 € | 2010 |
| 139 | TRANSPORTES EL MOSCA SA | MOLINA | 28.158.294,36 € | 2010 |
| 140 | AVICOLA LEVANTINA SA | MURCIA | 28.145.471,91 € | 2010 |
| 141 | REDYSER TRANSPORTE SL | MURCIA | 28.090.605,00 € | 2010 |
| 142 | PROBELTE SA | MURCIA | 27.952.423,88 € | 2010 |
| 143 | PASCUAL MARKETING SL | TORRE-PACHECO | 27.927.439,00 € | 2010 |
| 144 | BOVI SA | ALCANTARILLA | 27.807.954,12 € | 2010 |
| 145 | CEMENTOS LA CRUZ SL | ABANILLA | 27.578.633,00 € | 2011 |
| 146 | PUERTAS PADILLA SL | CARTAGENA | 27.428.080,13 € | 2010 |
| 147 | NATURAL SALADS SL | LORCA | 27.175.047,87 € | 2011 |
| 148 | BIBIANO Y CIA SL | POZO ESTRECHO | 26.935.770,08 € | 2010 |
| 149 | TANA SA | LOS RAMOS | 26.926.080,28 € | 2011 |
| 150 | PORCISAN SA | SANTOMERA | 26.740.569,85 € | 2010 |
