| POS. | EMPRESA | POBLACION | VENTAS | AÑO |
| 1951 | ANHERGRAU SL | BENIEL | 2.759.892,92 € | 2011 |
| 1952 | COISER JACOBO MARTINEZ SL | MURCIA | 2.759.629,44 € | 2011 |
| 1953 | VICTORIANO Y MULERO Y HNOS SL | LORCA | 2.758.294,36 € | 2011 |
| 1954 | AUXILIAR DE RECUPERACION DE ACTIVOS SA | MURCIA | 2.757.280,00 € | 2011 |
| 1955 | VICENTE SERRAT ANDREU SL | CARTAGENA | 2.752.936,62 € | 2011 |
| 1956 | PROMOCIONES EUGENIO BUENDIA S.L | FUENTE ALAMO | 2.752.907,55 € | 2011 |
| 1957 | GARCIA DE BULLAS SL | BULLAS | 2.750.271,16 € | Ant. |
| 1958 | LA COMODA MUEBLES SL | YECLA | 2.748.458,73 € | Ant. |
| 1959 | BODEGAS OLIVARES SL | JUMILLA | 2.746.747,17 € | 2011 |
| 1960 | RECUPERADOS DISANLUZ SL | LORCA | 2.745.803,92 € | 2011 |
| 1961 | CHABELI TRANS SL | SAN PEDRO | 2.744.652,52 € | 2011 |
| 1962 | EDIFICIOS TAMAROSA SL | MURCIA | 2.743.745,81 € | 2011 |
| 1963 | EE SS FORTUNA HERRERO Y PEREZ SL | FORTUNA | 2.742.469,18 € | Ant. |
| 1964 | SUPER MAPE SL | MURCIA | 2.741.424,98 € | 2010 |
| 1965 | RIEGOS Y TECNOLOGIA SL | AGUILAS | 2.740.097,10 € | 2011 |
| 1966 | TERMINAL MARITIMA DE CARTAGENA SL | CARTAGENA | 2.738.077,90 € | 2011 |
| 1967 | AEROBAÑO MURCIA S.L | LORQUI | 2.736.816,30 € | Ant. |
| 1968 | LORQUINA DE DISTRIBUCION Y BEBIDAS SL | LORCA | 2.736.453,82 € | 2011 |
| 1969 | ELECTRONICA RAYTE SL | MURCIA | 2.736.439,20 € | 2011 |
| 1970 | MAQ. CONSERVERA TOMAS GUILLEN SL | LORQUI | 2.735.697,32 € | 2011 |
| 1971 | KUASAR MOTOR SL | MURCIA | 2.735.148,51 € | Ant. |
| 1972 | PRODUCCIONES BIOLOGICAS SL | AGUILAS | 2.733.104,32 € | 2010 |
| 1973 | LIBECROM SA | MURCIA | 2.732.573,13 € | 2011 |
| 1974 | T.M. SILLERIAS SL | YECLA | 2.732.200,54 € | 2010 |
| 1975 | MIGUEL MUÑOZ OLIVARES SL | FUENTE ALAMO | 2.727.819,70 € | 2011 |
| 1976 | TALLERES GOMARIZ SA | LAS TORRES | 2.727.301,05 € | 2011 |
| 1977 | VIVIENDAS UNIFAMILIARES CARMONA SL | MURCIA | 2.724.658,60 € | Ant. |
| 1978 | ALOA SA | ALHAMA | 2.724.610,19 € | Ant. |
| 1979 | ESTACIONES DE SERVICIOS MOLERO SA | CARTAGENA | 2.722.956,45 € | Ant. |
| 1980 | HOBY VIAJES SL | CARAVACA | 2.722.370,78 € | 2010 |
| 1981 | ORGANIZACION FRIGORIFICA SA | TOTANA | 2.720.832,87 € | Ant. |
| 1982 | AMBULANCIAS MARTINEZ SL | CARTAGENA | 2.720.769,99 € | 2011 |
| 1983 | DIST. GAVINAS SL | MURCIA | 2.720.744,34 € | Ant. |
| 1984 | COMERCIAL MURCIANA DE BEBIDAS SL | MURCIA | 2.720.259,07 € | 2011 |
| 1985 | MATERIALES DE CONST. JUAN GARCIA SL | TORRE-PACHECO | 2.719.208,33 € | 2011 |
| 1986 | PROSER SL | MOLINA | 2.718.435,00 € | Ant. |
| 1987 | CHAMPIÑONES REQUENA SL | MURCIA | 2.717.022,56 € | 2010 |
| 1988 | GRUPO LOLLAN'S TORREMATA SL | CARAVACA | 2.715.958,12 € | 2011 |
| 1989 | CONSTRUCCIONES JUMICON SL | JUMILLA | 2.713.612,13 € | Ant. |
| 1990 | CARTHAGOVIN SL | CARTAGENA | 2.711.936,63 € | 2011 |
| 1991 | MATADERO EL CABEZO DE LA PLATA SL | MURCIA | 2.711.465,47 € | 2011 |
| 1992 | FRANCISCO DIAZ GABALDON SL | YECLA | 2.710.191,71 € | 2011 |
| 1993 | JOSE LUIS MUÑOZ E HIJOS SL | AGUILAS | 2.709.901,41 € | 2011 |
| 1994 | JADE MOTOR SL | CARTAGENA | 2.702.561,97 € | 2010 |
| 1995 | ENCARNACION AGUILAR LOPEZ SL | CARTAGENA | 2.702.336,47 € | 2011 |
| 1996 | NOVOHUECO SL | MURCIA | 2.701.934,56 € | Ant. |
| 1997 | HORMIGONES MAR MENOR SL | TORRE-PACHECO | 2.700.175,41 € | 2011 |
| 1998 | LUIS TORRES RUBIO SL | MURCIA | 2.699.892,72 € | 2011 |
| 1999 | MASILBE SL | MURCIA | 2.697.504,53 € | Ant. |
| 2000 | AGENCIA LATERAL 2008 SL | LORCA | 2.696.761,13 € | 2011 |
